{"id":5913,"date":"2023-02-08T11:43:43","date_gmt":"2023-02-08T16:43:43","guid":{"rendered":"https:\/\/gonaviance.com\/?p=5913"},"modified":"2023-12-05T10:28:26","modified_gmt":"2023-12-05T15:28:26","slug":"mutations-in-tumors-may-predict-response-to-immunotherapy","status":"publish","type":"post","link":"https:\/\/gonaviance.com\/es\/mutations-in-tumors-may-predict-response-to-immunotherapy\/","title":{"rendered":"Mutaciones \u201cdif\u00edciles de detectar\u201d en tumores pueden predecir la respuesta a la inmunoterapia"},"content":{"rendered":"<p>Los expertos en c\u00e1ncer han intentado, a veces sin \u00e9xito, utilizar el n\u00famero total de mutaciones en un tumor, llamado carga de mutaciones tumorales (TMB, por sus siglas en ingl\u00e9s), para predecir la respuesta de un paciente a la inmunoterapia. Ahora, los investigadores de Johns Hopkins han descubierto que es menos probable que un subconjunto de mutaciones dentro del TMB general, denominado \u201cmutaciones persistentes\u201d, se eliminen a medida que evoluciona el c\u00e1ncer, lo que hace que los tumores tengan m\u00e1s probabilidades de responder a la inmunoterapia. <span style=\"font-family: 'Gill Sans MT', 'Gill Sans', Calibri, sans-serif; font-size: 18px;\">Leer m\u00e1s <\/span><a style=\"font-family: 'Gill Sans MT', 'Gill Sans', Calibri, sans-serif; font-size: 18px;\" href=\"https:\/\/www.hopkinsmedicine.org\/news\/newsroom\/news-releases\/hard-to-lose-mutations-in-tumors-may-predict-response-to-immunotherapy\" target=\"_blank\" rel=\"noopener\">aqu\u00ed<\/a><span style=\"font-family: 'Gill Sans MT', 'Gill Sans', Calibri, sans-serif; font-size: 18px;\">.<\/span><\/p>","protected":false},"excerpt":{"rendered":"<p>Los expertos en c\u00e1ncer han intentado, a veces sin \u00e9xito, utilizar el n\u00famero total de mutaciones en un tumor, llamado [\u2026]<\/p>","protected":false},"author":102,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"class_list":["post-5913","post","type-post","status-publish","format-standard","hentry","category-news","role-caregiver","role-other","role-person-with-cancer","media-type-text"],"acf":[],"_links":{"self":[{"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/posts\/5913","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/users\/102"}],"replies":[{"embeddable":true,"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/comments?post=5913"}],"version-history":[{"count":0,"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/posts\/5913\/revisions"}],"wp:attachment":[{"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/media?parent=5913"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gonaviance.com\/es\/wp-json\/wp\/v2\/categories?post=5913"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}